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Telomere length homeostasis requires that telomerase levels are limiting
Stabilization of telomere length in germline and highly proliferative human cells is required for long-term survival and for the immortal phenotype of cancer-derived cells. This is achieved through expression of telomerase reverse transcriptase (TERT), which synthesizes telomeric repeats through rev...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2006
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1383536/ https://ncbi.nlm.nih.gov/pubmed/16424902 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600952 |
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