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Telomere length homeostasis requires that telomerase levels are limiting

Stabilization of telomere length in germline and highly proliferative human cells is required for long-term survival and for the immortal phenotype of cancer-derived cells. This is achieved through expression of telomerase reverse transcriptase (TERT), which synthesizes telomeric repeats through rev...

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Autors principals: Cristofari, Gaël, Lingner, Joachim
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1383536/
https://ncbi.nlm.nih.gov/pubmed/16424902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600952
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