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Comparison of Class A and D G Protein-Coupled Receptors: Common Features in Structure and Activation

All G protein-coupled receptors (GPCRs) share a common seven TM helix architecture and the ability to activate heterotrimeric G proteins. Nevertheless, these receptors have widely divergent sequences with no significant homology. We present a detailed structure–function comparison of the very diverg...

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Detalhes bibliográficos
Main Authors: Eilers, Markus, Hornak, Viktor, Smith, Steven O., Konopka, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1382269/
https://ncbi.nlm.nih.gov/pubmed/15966721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi047316u
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