No evidence for association of ataxia-telangiectasia mutated gene T2119C and C3161G amino acid substitution variants with risk of breast cancer

BACKGROUND: There is evidence that certain mutations in the double-strand break repair pathway ataxia-telangiectasia mutated gene act in a dominant-negative manner to increase the risk of breast cancer. There are also some reports to suggest that the amino acid substitution variants T2119C Ser707Pro...

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Main Authors: Spurdle, Amanda B, Hopper, John L, Chen, Xiaoqing, McCredie, Margaret RE, Giles, Graham G, Newman, Beth, Chenevix-Trench, Georgia, Khanna, KumKum
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2002
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC137935/
https://ncbi.nlm.nih.gov/pubmed/12473176
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