Internalization and recycling of 5-HT(2A) receptors activated by serotonin and protein kinase C-mediated mechanisms

Serotonin (5-HT), a major neurotransmitter, has a large number of G protein-coupled receptors in mammals. On activation by exposure to their ligand, 5-HT(2) receptor subtypes increase IP(3) levels and undergo desensitization and internalization. To visualize the receptor in cells during these proces...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Bhattacharyya, Samarjit, Puri, Sapna, Miledi, Ricardo, Panicker, Mitradas M.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 2002
Schlagworte:	Biological Sciences
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137907/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12388782/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.212517999
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