Internalization and recycling of 5-HT(2A) receptors activated by serotonin and protein kinase C-mediated mechanisms

Serotonin (5-HT), a major neurotransmitter, has a large number of G protein-coupled receptors in mammals. On activation by exposure to their ligand, 5-HT(2) receptor subtypes increase IP(3) levels and undergo desensitization and internalization. To visualize the receptor in cells during these proces...

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Detaylı Bibliyografya
Asıl Yazarlar: Bhattacharyya, Samarjit, Puri, Sapna, Miledi, Ricardo, Panicker, Mitradas M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2002
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC137907/
https://ncbi.nlm.nih.gov/pubmed/12388782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.212517999
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