Uterotropic response to the antidepressant fluoxetine (Prozac) is dependent on a functional serotonin transporter and circulating serotonin

Abstract Selective serotonin reuptake inhibitors (SSRI) are the most used antidepressants. However, they appear to pose a role as endocrine disrupting agents, particularly related to estrogen signaling. We sought to investigate the in vivo effects of fluoxetine, the most well-known SSRI, on uterine...

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Autors principals:	Rafael R. Domingues, Jessica Fox, Emma Day, Milo C. Wiltbank, Laura L. Hernandez
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2025-12-01
Col·lecció:	Scientific Reports
Matèries:	Endocrine disruption Estrogen signaling Selective serotonin reuptake inhibitor Serotonin transporter Uterotrophic assay
Accés en línia:	https://doi.org/10.1038/s41598-025-27477-w
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