Biological activity of the Helicobacter pylori virulence factor CagA is determined by variation in the tyrosine phosphorylation sites

Helicobacter pylori is a causative agent of gastritis and peptic ulcer. cagA(+) H. pylori strains are more virulent than cagA(−) strains and are associated with gastric carcinoma. The cagA gene product, CagA, is injected by the bacterium into gastric epithelial cells and subsequently undergoes tyros...

ver descrição completa

Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Higashi, Hideaki, Tsutsumi, Ryouhei, Fujita, Akiko, Yamazaki, Shiho, Asaka, Masahiro, Azuma, Takeshi, Hatakeyama, Masanori
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137900/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222375399
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!