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A simple physical model for binding energy hot spots in protein–protein complexes

Protein–protein recognition plays a central role in most biological processes. Although the structures of many protein–protein complexes have been solved in molecular detail, general rules describing affinity and selectivity of protein–protein interactions do not accurately account for the extremely...

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Detalles Bibliográficos
Main Authors: Kortemme, Tanja, Baker, David
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2002
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC137846/
https://ncbi.nlm.nih.gov/pubmed/12381794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202485799
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