Structure of the GCN5 histone acetyltransferase bound to a bisubstrate inhibitor
Histone acetyltransferases (HATs) use acetyl CoA to acetylate target lysine residues within histones and other transcription factors, such as the p53 tumor suppressor, to promote gene activation. HAT enzymes fall into subfamilies with divergence in sequence and substrate preference. Several HAT prot...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137837/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12391296/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.222373899 |
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