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Power of linkage versus association analysis of quantitative traits, by use of variance-components models, for sibship data.

Optimal design of quantitative-trait loci (QTL) mapping studies requires a precise understanding of the power of QTL linkage versus QTL association analysis, under a range of different conditions. In this article, we investigate the power of QTL linkage and association analyses for simple random sib...

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Autors principals: Sham, P C, Cherny, S S, Purcell, S, Hewitt, J K
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1378020/
https://ncbi.nlm.nih.gov/pubmed/10762547
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