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FMR1 CGG-repeat instability in single sperm and lymphocytes of fragile-X premutation males.

To determine the meiotic instability of the CGG-triplet repeat in the fragile-X gene, FMR1, we examined the size of the repeat in single sperm from four premutation males. The males had CGG-repeat sizes of 68, 75, 78, and 100, as determined in peripheral blood samples. All samples showed a broad ran...

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Main Authors: Nolin, S L, Houck, G E, Gargano, A D, Blumstein, H, Dobkin, C S, Brown, W T
格式: Artigo
語言:Inglês
出版: 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377974/
https://ncbi.nlm.nih.gov/pubmed/10441574
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