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Instability of the CGG repeat and expression of the FMR1 protein in a male fragile X patient with a lung tumor.

The molecular mechanism of the fragile X syndrome is based on the expansion of an CGG repeat in the 5' UTR of the FMR1 gene in the majority of fragile X patients. This repeat displays instability both between individuals and within an individual. We studied the instability of the CGG repeat and...

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Detalhes bibliográficos
Main Authors: de Graaff, E, Willemsen, R, Zhong, N, de Die-Smulders, C E, Brown, W T, Freling, G, Oostra, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1801284/
https://ncbi.nlm.nih.gov/pubmed/7668289
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