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Molecular basis for hypertension in the "type II variant" of apparent mineralocorticoid excess.

The syndrome of apparent mineralocorticoid excess (AME) is a heritable form of hypertension in which cortisol acts as a potent mineralocorticoid. The type I variant results in a severe clinical and biochemical phenotype and arises because of mutations in the gene encoding the type 2 isozyme of 11bet...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Li, A, Tedde, R, Krozowski, Z S, Pala, A, Li, K X, Shackleton, C H, Mantero, F, Palermo, M, Stewart, P M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1377297/
https://ncbi.nlm.nih.gov/pubmed/9683587
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