Syndrome of apparent mineralocorticoid excess. A defect in the cortisol-cortisone shuttle.
The first adult case of 11 beta-hydroxysteroid dehydrogenase (11 beta-OHSD) deficiency is described. The impaired conversion of cortisol to cortisone (indicated by urinary cortisol and cortisone metabolites and failure to metabolize 11 alpha-[3H]cortisol to [3H]H2O), was associated with hypertension...
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| Publicado no: | J Clin Invest |
|---|---|
| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
1988
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC303514/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3164727/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI113592 |
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