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Genetic heterogeneity and penetrance analysis of the BRCA1 and BRCA2 genes in breast cancer families. The Breast Cancer Linkage Consortium.

The contribution of BRCA1 and BRCA2 to inherited breast cancer was assessed by linkage and mutation analysis in 237 families, each with at least four cases of breast cancer, collected by the Breast Cancer Linkage Consortium. Families were included without regard to the occurrence of ovarian or other...

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Detalhes bibliográficos
Main Authors: Ford, D, Easton, D F, Stratton, M, Narod, S, Goldgar, D, Devilee, P, Bishop, D T, Weber, B, Lenoir, G, Chang-Claude, J, Sobol, H, Teare, M D, Struewing, J, Arason, A, Scherneck, S, Peto, J, Rebbeck, T R, Tonin, P, Neuhausen, S, Barkardottir, R, Eyfjord, J, Lynch, H, Ponder, B A, Gayther, S A, Zelada-Hedman, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1376944/
https://ncbi.nlm.nih.gov/pubmed/9497246
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