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Promiscuous methylation of non-canonical DNA sites by HaeIII methyltransferase

The cytosine C5 methyltransferase M.HaeIII recognises and methylates the central cytosine of its canonical site GGCC. Here we report that M.HaeIII can also, with lower efficiency, methylate cytosines located in a wide range of non-canonical sequences. Using bisulphite sequencing we mapped the methyl...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Cohen, Helen M., Tawfik, Dan S., Griffiths, Andrew D.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2002
Teme:
Online pristup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137429/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12202773/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf507
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