Promiscuous methylation of non-canonical DNA sites by HaeIII methyltransferase
The cytosine C5 methyltransferase M.HaeIII recognises and methylates the central cytosine of its canonical site GGCC. Here we report that M.HaeIII can also, with lower efficiency, methylate cytosines located in a wide range of non-canonical sequences. Using bisulphite sequencing we mapped the methyl...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2002
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12202773/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf507 |
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