Promiscuous methylation of non-canonical DNA sites by HaeIII methyltransferase

The cytosine C5 methyltransferase M.HaeIII recognises and methylates the central cytosine of its canonical site GGCC. Here we report that M.HaeIII can also, with lower efficiency, methylate cytosines located in a wide range of non-canonical sequences. Using bisulphite sequencing we mapped the methyl...

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Библиографические подробности

Опубликовано в::	Nucleic Acids Res
Главные авторы:	Cohen, Helen M., Tawfik, Dan S., Griffiths, Andrew D.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Oxford University Press 2002
Предметы:	Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137429/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12202773/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf507
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