Distinct domains in the CArG-box binding factor A destabilize tetraplex forms of the fragile X expanded sequence d(CGG)(n)
Formation of hairpin or tetraplex structures of the FMR1 gene d(CGG)(n) sequence triggers its expansion, setting off fragile X syndrome. In searching for proteins that destabilize d(CGG)(n) secondary structures we purified from rat liver quadruplex telomeric DNA binding protein 42 (qTBP42) that disr...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12202751/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf506 |
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