Distinct domains in the CArG-box binding factor A destabilize tetraplex forms of the fragile X expanded sequence d(CGG)(n)

Formation of hairpin or tetraplex structures of the FMR1 gene d(CGG)(n) sequence triggers its expansion, setting off fragile X syndrome. In searching for proteins that destabilize d(CGG)(n) secondary structures we purified from rat liver quadruplex telomeric DNA binding protein 42 (qTBP42) that disr...

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Bibliografische gegevens

Gepubliceerd in:	Nucleic Acids Res
Hoofdauteurs:	Weisman-Shomer, Pnina, Cohen, Esther, Fry, Michael
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Oxford University Press 2002
Onderwerpen:	Article
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137428/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12202751/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf506
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