Polyamine structural effects on the induction and stabilization of liquid crystalline DNA: potential applications to DNA packaging, gene therapy and polyamine therapeutics

DNA undergoes condensation, conformational transitions, aggregation and resolubilization in the presence of polyamines, positively charged organic molecules present in all cells. Under carefully controlled environmental conditions, DNA can also transform to a liquid crystalline state in vitro. We un...

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Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Saminathan, M., Thomas, Thresia, Shirahata, Akira, Pillai, C. K. S., Thomas, T. J.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 2002
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137425/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12202757/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf503
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