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Radiation Therapy Potentiates Effective Oncolytic Viral Therapy in the Treatment of Lung Cancer
BACKGROUND: Replication-competent oncolytic herpes simplex viruses (HSV) with deletion of the γ(1)34.5 gene preferentially replicate in and kill malignant cells. γ(1)34.5 codes for ICP 34.5, a protein that enhances viral replication, and is homologous to Growth Arrest and DNA damage Protein 34 (GADD...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1373787/ https://ncbi.nlm.nih.gov/pubmed/16039175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.athoracsur.2005.01.048 |
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