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Novel thermostable Y-family polymerases: applications for the PCR amplification of damaged or ancient DNAs
For many years, Taq polymerase has served as the stalwart enzyme in the PCR amplification of DNA. However, a major limitation of Taq is its inability to amplify damaged DNA, thereby restricting its usefulness in forensic applications. In contrast, Y-family DNA polymerases, such as Dpo4 from Sulfolob...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1373694/ https://ncbi.nlm.nih.gov/pubmed/16488882 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkj512 |
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