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D-MEKK1, the Drosophila orthologue of mammalian MEKK4/MTK1, and Hemipterous/D-MKK7 mediate the activation of D-JNK by cadmium and arsenite in Schneider cells

BACKGROUND: The family of c-Jun NH(2)-terminal kinases (JNK) plays important roles in embryonic development and in cellular responses to stress. Toxic metals and their compounds are potent activators of JNK in mammalian cells. The mechanism of mammalian JNK activation by cadmium and sodium arsenite...

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Detalhes bibliográficos
Main Authors: Ryabinina, Olga P, Subbian, Ezhilkani, Iordanov, Mihail S
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1373652/
https://ncbi.nlm.nih.gov/pubmed/16451733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-7-7
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