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Localization of DNA polymerases η and ι to the replication machinery is tightly co-ordinated in human cells

Y-family DNA polymerases can replicate past a variety of damaged bases in vitro but, with the exception of DNA polymerase η (polη), which is defective in xeroderma pigmentosum variants, there is little information on the functions of these polymerases in vivo. Here, we show that DNA polymerase ι (po...

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Autors principals: Kannouche, Patricia, Fernández de Henestrosa, Antonio R., Coull, Barry, Vidal, Antonio E., Gray, Colin, Zicha, Daniel, Woodgate, Roger, Lehmann, Alan R.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2002
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC137208/
https://ncbi.nlm.nih.gov/pubmed/12426396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf618
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