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Rab-αGDI activity is regulated by a Hsp90 chaperone complex

The Rab-specific αGDP-dissociation inhibitor (αGDI) regulates the recycling of Rab GTPases. We have now identified a novel αGDI complex from synaptic membranes that contains three chaperone components: Hsp90, Hsc70 and cysteine string protein (CSP). We find that the αGDI–chaperone complex is dissoci...

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Detalhes bibliográficos
Main Authors: Sakisaka, Toshiaki, Meerlo, Timo, Matteson, Jeanne, Plutner, Helen, Balch, William E.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137195/
https://ncbi.nlm.nih.gov/pubmed/12426384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf603
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