A carregar...
Crystal structure of actinomycin D bound to the CTG triplet repeat sequences linked to neurological diseases
The potent anticancer drug actinomycin D (ActD) acts by binding to DNA GpC sequences, thereby interfering with essential biological processes including replication, transcription and topoisomerase. Certain neurological diseases are correlated with expansion of (CTG)(n) trinucleotide sequences, which...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC137167/ https://ncbi.nlm.nih.gov/pubmed/12433994 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|