Role of tumor suppressor p53 domains in selective binding to supercoiled DNA
We showed previously that bacterially expressed full-length human wild-type p53b(1–393) binds selectively to supercoiled (sc)DNA in sc/linear DNA competition experiments, a process we termed supercoil-selective (SCS) binding. Using p53 deletion mutants and pBluescript scDNA (lacking the p53 recognit...
Kaydedildi:
| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
2002
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137164/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12434001/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf616 |
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