Role of tumor suppressor p53 domains in selective binding to supercoiled DNA
We showed previously that bacterially expressed full-length human wild-type p53b(1–393) binds selectively to supercoiled (sc)DNA in sc/linear DNA competition experiments, a process we termed supercoil-selective (SCS) binding. Using p53 deletion mutants and pBluescript scDNA (lacking the p53 recognit...
Gespeichert in:
| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2002
|
| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137164/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12434001/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkf616 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|