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G4 DNA unwinding by BLM and Sgs1p: substrate specificity and substrate-specific inhibition

To understand the specific genetic instabilities associated with deficiencies in RecQ family helicases, we have studied the substrate preferences of two closely related members of this family, human BLM and Saccharomyces cerevisiae Sgs1p. Here we show that both BLM and Sgs1p preferentially unwind G4...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Huber, Michael D., Lee, Damian C., Maizels, Nancy
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Oxford University Press 2002
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC137114/
https://ncbi.nlm.nih.gov/pubmed/12235379
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