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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
A large number of miRNAs have recently been discovered in plants and animals. Development of reverse genetic approaches that act to inhibit microRNA function would facilitate the study of this new class of noncoding RNA. Here we show that 2′-O-methyl oligoribonucleotides, but not 2′-deoxyoligonucleo...
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Format: | Artigo |
Sprache: | Inglês |
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Copyright 2004 by RNA Society
2004
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370948/ https://ncbi.nlm.nih.gov/pubmed/14970398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5235104 |
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