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Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing

A large number of miRNAs have recently been discovered in plants and animals. Development of reverse genetic approaches that act to inhibit microRNA function would facilitate the study of this new class of noncoding RNA. Here we show that 2′-O-methyl oligoribonucleotides, but not 2′-deoxyoligonucleo...

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Hlavní autoři: MEISTER, GUNTER, LANDTHALER, MARKUS, DORSETT, YAIR, TUSCHL, THOMAS
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2004 by RNA Society 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370948/
https://ncbi.nlm.nih.gov/pubmed/14970398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5235104
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