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Characterization of deadenylation in trypanosome extracts and its inhibition by poly(A)-binding protein Pab1p

The stability of mRNAs is an important point in the regulation of gene expression in eukaryotes. The mRNA turnover pathways have been identified in yeast and mammals. However, mRNA turnover pathways in trypanosomes have not been widely studied. Deadenylation is the first step in the major mRNA turno...

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Bibliographic Details
Main Authors: MILONE, JOSEPH, WILUSZ, JEFFREY, BELLOFATTO, VIVIAN
Format: Artigo
Language:Inglês
Published: Copyright 2004 by RNA Society 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370940/
https://ncbi.nlm.nih.gov/pubmed/14970390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5180304
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