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Evidence for a base triple in the free HIV-1 TAR RNA

We propose the existence of a novel base triple in the HIV-1 TAR hairpin. This triple is supported by covariation of loop residue 31 with residue 22, which is part of an unusual base pair with U40 below the 3-nucleotide bulge. A set of mutants was constructed to test the involvement of bases A22, U3...

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Detalhes bibliográficos
Main Authors: HUTHOFF, HENDRIK, GIRARD, FREDERIC, WIJMENGA, SYBREN S., BERKHOUT, BEN
Formato: Artigo
Idioma:Inglês
Publicado em: Copyright 2004 by RNA Society 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370937/
https://ncbi.nlm.nih.gov/pubmed/14970387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5161304
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