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Modifications and deletions of helices within the hairpin ribozyme–substrate complex: An active ribozyme lacking helix 1

Within the hairpin ribozyme, structural elements required for formation of the active tertiary structure are localized in two independently folding domains, each consisting of an internal loop flanked by helical elements. Here, we present results of a systematic examination of the relationship betwe...

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Autors principals: PINARD, ROBERT, LAMBERT, DOMINIC, POTHIAWALA, GULNAR, MAJOR, FRANÇOIS, BURKE, JOHN M.
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2004 by RNA Society 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370935/
https://ncbi.nlm.nih.gov/pubmed/14970385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5650904
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