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SNP genotyping on pooled DNAs: comparison of genotyping technologies and a semi automated method for data storage and analysis

We have compared the accuracy, efficiency and robustness of three methods of genotyping single nucleotide polymorphisms on pooled DNAs. We conclude that (i) the frequencies of the two alleles in pools should be corrected with a factor for unequal allelic amplification, which should be estimated from...

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Published in:Nucleic Acids Res
Main Authors: Le Hellard, Stéphanie, Ballereau, Stéphane J., Visscher, Peter M., Torrance, Helen S., Pinson, Jeni, Morris, Stewart W., Thomson, Marian L., Semple, Colin A. M., Muir, Walter J., Blackwood, Douglas H. R., Porteous, David J., Evans, Kathryn L.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2002
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NAR Methods Online
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12140336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf070
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