SNP genotyping on pooled DNAs: comparison of genotyping technologies and a semi automated method for data storage and analysis

We have compared the accuracy, efficiency and robustness of three methods of genotyping single nucleotide polymorphisms on pooled DNAs. We conclude that (i) the frequencies of the two alleles in pools should be corrected with a factor for unequal allelic amplification, which should be estimated from...

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Main Authors: Le Hellard, Stéphanie, Ballereau, Stéphane J., Visscher, Peter M., Torrance, Helen S., Pinson, Jeni, Morris, Stewart W., Thomson, Marian L., Semple, Colin A. M., Muir, Walter J., Blackwood, Douglas H. R., Porteous, David J., Evans, Kathryn L.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2002
主題:
NAR Methods Online
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC137092/
https://ncbi.nlm.nih.gov/pubmed/12140336
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