SNP genotyping on pooled DNAs: comparison of genotyping technologies and a semi automated method for data storage and analysis

We have compared the accuracy, efficiency and robustness of three methods of genotyping single nucleotide polymorphisms on pooled DNAs. We conclude that (i) the frequencies of the two alleles in pools should be corrected with a factor for unequal allelic amplification, which should be estimated from...

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Detalhes bibliográficos
Main Authors: Le Hellard, Stéphanie, Ballereau, Stéphane J., Visscher, Peter M., Torrance, Helen S., Pinson, Jeni, Morris, Stewart W., Thomson, Marian L., Semple, Colin A. M., Muir, Walter J., Blackwood, Douglas H. R., Porteous, David J., Evans, Kathryn L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
Assuntos:
NAR Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC137092/
https://ncbi.nlm.nih.gov/pubmed/12140336
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