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SNP genotyping on pooled DNAs: comparison of genotyping technologies and a semi automated method for data storage and analysis

We have compared the accuracy, efficiency and robustness of three methods of genotyping single nucleotide polymorphisms on pooled DNAs. We conclude that (i) the frequencies of the two alleles in pools should be corrected with a factor for unequal allelic amplification, which should be estimated from...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Principais autores: Le Hellard, Stéphanie, Ballereau, Stéphane J., Visscher, Peter M., Torrance, Helen S., Pinson, Jeni, Morris, Stewart W., Thomson, Marian L., Semple, Colin A. M., Muir, Walter J., Blackwood, Douglas H. R., Porteous, David J., Evans, Kathryn L.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2002
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC137092/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12140336/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gnf070
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