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Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase

Polynucleotide kinase-phosphatase (Pnkp) from Clostridium thermocellum catalyzes ATP-dependent phosphorylation of 5′-OH termini of DNA or RNA polynucleotides and Ni(2+)/Mn(2+)-dependent dephosphorylation of 2′,3′ cyclic phosphate, 2′-phosphate, and 3′-phosphate ribonucleotides. CthPnkp is an 870-ami...

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Bibliographic Details
Main Authors: KEPPETIPOLA, NIROSHIKA, SHUMAN, STEWART
Format: Artigo
Language:Inglês
Published: Copyright 2006 by RNA Society 2006
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370887/
https://ncbi.nlm.nih.gov/pubmed/16301605
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2196406
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