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Mechanism of the phosphatase component of Clostridium thermocellum polynucleotide kinase-phosphatase
Polynucleotide kinase-phosphatase (Pnkp) from Clostridium thermocellum catalyzes ATP-dependent phosphorylation of 5′-OH termini of DNA or RNA polynucleotides and Ni(2+)/Mn(2+)-dependent dephosphorylation of 2′,3′ cyclic phosphate, 2′-phosphate, and 3′-phosphate ribonucleotides. CthPnkp is an 870-ami...
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Main Authors: | , |
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Format: | Artigo |
Language: | Inglês |
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Copyright 2006 by RNA Society
2006
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Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370887/ https://ncbi.nlm.nih.gov/pubmed/16301605 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2196406 |
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