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Functional characterization of the SOFA delta ribozyme
Molecular engineering has led to the development of a novel target-dependent riboswitch that increases δribozyme fidelity. This δ ribozyme possesses a specific on/off adapter (SOFA) that switches the cleavage activity from off (a “safety lock”) to on solely in the presence of the desired RNA substra...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Copyright 2005 by RNA Society
2005
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370874/ https://ncbi.nlm.nih.gov/pubmed/16251383 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2112705 |
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