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Target-dependent on/off switch increases ribozyme fidelity
Ribozymes, RNA molecules that catalyze the cleavage of RNA substrates, provide an interesting alternative to the RNA interference (RNAi) approach to gene inactivation, especially given the fact that RNAi seems to trigger an immunological response. Unfortunately, the limited substrate specificity of...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2005
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC549572/ https://ncbi.nlm.nih.gov/pubmed/15731344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki278 |
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