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Target-dependent on/off switch increases ribozyme fidelity

Ribozymes, RNA molecules that catalyze the cleavage of RNA substrates, provide an interesting alternative to the RNA interference (RNAi) approach to gene inactivation, especially given the fact that RNAi seems to trigger an immunological response. Unfortunately, the limited substrate specificity of...

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Sonraí Bibleagrafaíochta
Main Authors: Bergeron, Lucien Junior, Perreault, Jean-Pierre
Formáid: Artigo
Teanga:Inglês
Foilsithe: Oxford University Press 2005
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC549572/
https://ncbi.nlm.nih.gov/pubmed/15731344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gki278
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