Silencing of Amyloid Precursor Protein Expression Using a New Engineered Delta Ribozyme

Alzheimer's disease (AD) etiological studies suggest that an elevation in amyloid-β peptides (Aβ) level contributes to aggregations of the peptide and subsequent development of the disease. The major constituent of these amyloid peptides is the 1 to 40–42 residue peptide (Aβ (40−42)) derived fr...

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Bibliografiske detaljer
Main Authors: Ben Aissa, Manel, April, Marie-Claude, Bergeron, Lucien-Junior, Perreault, Jean-Pierre, Levesque, Georges
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3296272/
https://ncbi.nlm.nih.gov/pubmed/22482079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/947147
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