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Evidence for an RNA chaperone function of polypyrimidine tract-binding protein in picornavirus translation

The cellular polypyrimidine tract-binding protein (PTB) is recruited by the genomic RNAs of picornaviruses to stimulate translation initiation at their internal ribosome entry site (IRES) elements. We investigated the contribution of the individual RNA recognition motif (RRM) domains of PTB to its i...

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Main Authors: SONG, YUTONG, TZIMA, ELENI, OCHS, KERSTIN, BASSILI, GERGIS, TRUSHEIM, HEIDI, LINDER, MONICA, PREISSNER, KLAUS T., NIEPMANN, MICHAEL
Formato: Artigo
Idioma:Inglês
Publicado: Copyright 2005 by RNA Society 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370870/
https://ncbi.nlm.nih.gov/pubmed/16314455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7430405
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