Further evidence that ribavirin interacts with eIF4E

This commentary discusses the recent reports in RNA by Yan and colleagues and Westman and colleagues of the apparent failure of ribavirin to bind to recombinant eIF4E and inhibit 7-methyl guanosine cap-dependent exogenous mRNA translation of cell extracts in vitro. Measuring binding by using affinit...

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Autors principals: KENTSIS, ALEX, VOLPON, LAURENT, TOPISIROVIC, IVAN, SOLL, CLIFFORD E., CULJKOVIC, BILJANA, SHAO, LING, BORDEN, KATHERINE L.B.
Format: Artigo
Idioma:Inglês
Publicat: Copyright 2005 by RNA Society 2005
Matèries:
Letter to the Editor
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370864/
https://ncbi.nlm.nih.gov/pubmed/16251386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2238705
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