Effects of nucleotide substitution and modification on the stability and structure of helix 69 from 28S rRNA

The helix 69 (H69) region of the large subunit (28S) rRNA of Homo sapiens contains five pseudouridine (Ψ) residues out of 19 total nucleotides (26%), three of which are universally or highly conserved. In this study, the effects of this abundant modified nucleotide on the structure and stability of...

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Bibliographic Details
Main Authors: SUMITA, MINAKO, DESAULNIERS, JEAN-PAUL, CHANG, YU-CHENG, CHUI, HELEN M.-P., CLOS, LAWRENCE, CHOW, CHRISTINE S.
Format: Artigo
Language:Inglês
Published: Copyright 2005 by RNA Society 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370825/
https://ncbi.nlm.nih.gov/pubmed/16120833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2320605
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