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Effects of nucleotide substitution and modification on the stability and structure of helix 69 from 28S rRNA

The helix 69 (H69) region of the large subunit (28S) rRNA of Homo sapiens contains five pseudouridine (Ψ) residues out of 19 total nucleotides (26%), three of which are universally or highly conserved. In this study, the effects of this abundant modified nucleotide on the structure and stability of...

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Hlavní autoři: SUMITA, MINAKO, DESAULNIERS, JEAN-PAUL, CHANG, YU-CHENG, CHUI, HELEN M.-P., CLOS, LAWRENCE, CHOW, CHRISTINE S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2005 by RNA Society 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370825/
https://ncbi.nlm.nih.gov/pubmed/16120833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2320605
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