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In vivo excision of a single targeted nucleotide from an mRNA by a trans excision-splicing ribozyme
We have previously reported the development of a group I intron-derived ribozyme that can bind an exogenous RNA substrate and excise from that substrate an internal segment in vitro, which allows for sequence-specific modification of RNA molecules. In this report, the activity of this trans excision...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Copyright 2005 by RNA Society
2005
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370774/ https://ncbi.nlm.nih.gov/pubmed/15872183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.2050505 |
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