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Sequence characteristics of functional siRNAs
RNA interference in mammalian cells is actively used to conduct genetic screens, to identify and to validate targets, and to elucidate regulators and modifiers of cellular pathways. To ensure the specificity and efficacy of the active 21mer siRNA molecules, it is pertinent to develop a strategy for...
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| Autores principales: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Copyright 2005 by RNA Society
2005
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370771/ https://ncbi.nlm.nih.gov/pubmed/15923373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7275905 |
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