Sequence characteristics of functional siRNAs

RNA interference in mammalian cells is actively used to conduct genetic screens, to identify and to validate targets, and to elucidate regulators and modifiers of cellular pathways. To ensure the specificity and efficacy of the active 21mer siRNA molecules, it is pertinent to develop a strategy for...

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Main Authors: JAGLA, BERND, AULNER, NATHALIE, KELLY, PETER D., SONG, DA, VOLCHUK, ALLEN, ZATORSKI, ANDRZEJ, SHUM, DAVID, MAYER, THOMAS, DE ANGELIS, DINO A., OUERFELLI, OUATHEK, RUTISHAUSER, URS, ROTHMAN, JAMES E.
格式: Artigo
語言:Inglês
出版: Copyright 2005 by RNA Society 2005
主題:
Bioinformatics
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370771/
https://ncbi.nlm.nih.gov/pubmed/15923373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7275905
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