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Transfer-messenger RNA unfolds as it transits the ribosome

In bacteria, translation of mRNAs lacking stop codons produces truncated polypeptides and traps ribosomes in unproductive complexes. Potentially harmful truncated proteins are tagged with short peptides encoded by the mRNA-like domain of tmRNA and targeted for digestion by housekeeping proteases. We...

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Bibliographic Details
Main Authors: WOWER, IWONA K., ZWIEB, CHRISTIAN, WOWER, JACEK
Format: Artigo
Language:Inglês
Published: Copyright 2005 by RNA Society 2005
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370753/
https://ncbi.nlm.nih.gov/pubmed/15811920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7269305
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