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Transfer-messenger RNA unfolds as it transits the ribosome
In bacteria, translation of mRNAs lacking stop codons produces truncated polypeptides and traps ribosomes in unproductive complexes. Potentially harmful truncated proteins are tagged with short peptides encoded by the mRNA-like domain of tmRNA and targeted for digestion by housekeeping proteases. We...
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Formato: | Artigo |
Idioma: | Inglês |
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Copyright 2005 by RNA Society
2005
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1370753/ https://ncbi.nlm.nih.gov/pubmed/15811920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.7269305 |
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